What Is Trigeminal Neuralgia?
Trigeminal Neuralgia (TN) is a chronic pain condition affecting the trigeminal nerve — the fifth cranial nerve, and the largest of the cranial nerves. The trigeminal nerve carries sensation from the face to the brain, covering three divisions: the forehead and eye (V1), the cheek and upper jaw (V2), and the lower jaw and chin (V3).
TN causes sudden, severe, electric shock-like or stabbing facial pain that comes without warning and disappears as quickly as it arrived. The pain is typically on one side of the face and lasts from a fraction of a second to a few minutes. Between attacks, there may be no pain at all. However, attacks may occur many times a day and can be completely disabling.
Trigeminal Neuralgia is considered one of the most painful conditions known to medicine — it has been called the “suicide disease” because of the severity of untreated pain. However, with modern treatment — particularly MVD surgery — most patients can achieve long-term, durable pain relief.
Symptoms, Triggers & Causes of TN
Characteristic Symptoms
Common Triggers
What Causes Trigeminal Neuralgia?
In the majority of TN patients, a blood vessel — usually the Superior Cerebellar Artery (SCA) or Anterior Inferior Cerebellar Artery (AICA) — presses against the trigeminal nerve root at its entry zone into the brainstem. This chronic pulsatile compression causes demyelination (damage to the protective sheath) of the nerve fibres, leading to abnormal electrical discharge and the characteristic pain.
MS plaques can form at the trigeminal nucleus or nerve, causing TN. MS-related TN is more often bilateral. MRI identifies MS plaques and distinguishes MS-TN from classical vascular TN.
Occasionally a tumour at the cerebellopontine angle (acoustic neuroma, meningioma) or a vascular malformation compresses the trigeminal nerve. MRI identifies these secondary causes and guides treatment planning.
Trigeminal Neuralgia Treatment at KG Hospital
KG Hospital offers the complete range of Trigeminal Neuralgia treatments — from first-line medications through to definitive surgical cure. Treatment is selected based on patient age, general health, MRI findings, and preference.
Medication — First Line
Carbamazepine (Tegretol) or Oxcarbazepine are the first-line treatments. They reduce nerve firing and control pain in most patients initially. Over time, doses need to increase and side effects (drowsiness, dizziness, hyponatraemia) may become intolerable. When medications fail, surgical options are considered.
Microvascular Decompression (MVD)
Gold-standard surgery. Small posterior fossa craniotomy behind the ear. Offending vessel identified, repositioned, and a soft Teflon pad placed between vessel and nerve. 80–90% long-term pain-free rate. Facial sensation fully preserved. Best option for fit patients.
Glycerol Rhizotomy
Percutaneous minimally invasive procedure. Thin needle guided under X-ray fluoroscopy through the cheek to the trigeminal cistern at the skull base. Glycerol injected to selectively damage pain-carrying fibres. Day procedure. ~80% initial pain relief. May need repetition as pain can recur.
Radiofrequency Thermal Lesioning
Percutaneous procedure under fluoroscopic guidance. A probe is advanced to the trigeminal ganglion and radio-frequency heat is applied to selectively destroy pain fibres. Provides 3–4 years of relief. Some facial numbness expected post-procedure. Day procedure.
Microvascular Decompression (MVD) The Definitive Treatment
Microvascular Decompression (MVD) is the most effective and durable treatment for Trigeminal Neuralgia and addresses the root cause directly: the blood vessel compressing the trigeminal nerve root. It is the only TN treatment that does not damage the nerve itself.
The procedure is performed under general anaesthesia through a small craniotomy behind the ear (posterior fossa approach). The neurosurgeon — using the TIVATO 700 surgical microscope for magnification and illumination — identifies the trigeminal nerve root at its entry into the brainstem. The offending blood vessel is gently separated from the nerve and a soft Teflon pad is placed between them to prevent re-contact. The craniotomy is then closed.
There is no destruction of any part of the trigeminal nerve. Facial sensation is fully preserved. Pain relief is typically immediate upon waking from anaesthesia in most patients.
MVD is preferred for: patients in good general health with classical TN (vascular compression confirmed on MRI), younger patients requiring long-term durable relief, patients who have failed medication, and patients for whom facial numbness (a consequence of ablative procedures) would be unacceptable.
Who is a Candidate for Each Treatment?
Treatment selection depends on general health, age, MRI findings, medication history, and the patient’s priorities. Below is a guide — your neurosurgeon will review your specific situation.
Your MVD Patient Journey at KG Hospital
From first consultation to return to normal life — here is what a typical MVD patient journey looks like at KG Hospital Coimbatore.